منابع مشابه
Hypnotic dreams as a lens into hypnotic dynamics.
The hypnotic relationship is an important parameter for both experimental and therapeutic contexts. Hypnotic dreams may serve as a lens to examine the hypnotic relationship. By answering 5 questions per item, 70 judges rated 12 accounts of brief hypnotic dreams conducted as part of the Stanford Hypnotic Susceptibility Scale, Form C. The data show that the judges were able to correctly discern h...
متن کاملA Multifaceted GABAA Receptor Modulator: Functional Properties and Mechanism of Action of the Sedative-Hypnotic and Recreational Drug Methaqualone (Quaalude).
In the present study, we have elucidated the functional characteristics and mechanism of action of methaqualone (2-methyl-3-o-tolyl-4(3H)-quinazolinone, Quaalude), an infamous sedative-hypnotic and recreational drug from the 1960s-1970s. Methaqualone was demonstrated to be a positive allosteric modulator at human α1,2,3,5β2,3γ2S GABAA receptors (GABAARs) expressed in Xenopus oocytes, whereas it...
متن کاملThe use of trazodone as a hypnotic: a critical review.
BACKGROUND The last few years have seen a remarkable rise in the off-label use of trazodone for inducing sleep in nondepressed patients, to a degree that it is prescribed for this purpose as commonly as the leading hypnotic. In view of this widespread popularity, it seems prudent to review what is known of the safety and efficacy of trazodone when used in this context. DATA SOURCES AND SELECT...
متن کاملHeart-rate variability as a quantitative measure of hypnotic depth.
The authors investigated whether heart-rate variability can serve as a device for real-time quantitative measurement of hypnotic depth. This study compared the continuous self-rated hypnotic depth (SRHD) of 10 volunteers with heart rate, amplitude, and frequency changes from a time-frequency analysis of heart-rate variability (HRV). The authors found significant linear relationships between SRH...
متن کاملTreatment of Methaqualone overdose with resin hemoperfusion.
We recently utilized the technique of resin hemoperfusion (employing an Amberlite XAD-4 resin cartridge) to remove drug from a patient i deep coma after an estimated ingestion of greater than 4.5 grams of methaqualone. At plasma flow rates of 204 ml/min, the mean value for plasma clearance of methaqualone was 179 ml/min. The amount of methaqualone recovered from the cartridge at the end of the ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1961
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5220.171